Fertility
following IPAA
•Only recently have
studies examined the impact of IPAA on
female fertility
•Olsen et
al . (1999 and 2002)
–Significantly
fewer pregnancies were observed than expected
in a cohort of 250 Danish females (34 vs. 69; OR 0.49)
–Fecundability
(probability of becoming pregnant per month on unprotected intercourse) was significantly lower after IPAA compared to prior to the diagnosis of UC, prior to surgery and to a reference population