Predictive Value of CRP and Other Inflammatory Markers: LDL <130 mg/dL
Ridker et al. N Engl J Med 2000;342:836–843
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Text Box: Relative risk of future coronary events
Relative risk of future
coronary events
Quartile of inflammatory marker
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hs-CRP
SAA
IL-6
sICAM-1
Predictive value of CRP and other inflammatory markers: LDL <130 mg/dL
This phenomenon is best seen in this slide, which demonstrates marked predictive value for four inflammatory markers:  ICAM-1, interleukin-6, serum amyloid A, and hs-CRP, even among the apparently healthy women in the Women's Health Study whose LDL cholesterol was already at target according to NCEP guidelines, that is to say, less than 130 mg/dL in a primary-prevention setting.

Reference:
Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000;342:836-843.