Eliminating periodontitis does not lower coronary heart disease risk

המידע באדיבות מדיקונטקסט
Last Updated: 2001-07-24 12:28:46 EDT (Reuters Health)

WESTPORT, CT (Reuters Health) – Elimination of chronic dental infection does nothing to lower the risk of coronary heart disease (CHD), according to an analysis of data from the first National Health and Nutrition Examination Survey (NHANES I) Epidemiological Follow-up Study (NHEFS).

Periodontal disease has previously been linked with CHD (see Reuters Health report, November 13, 2000), but other analyses have contradicted the association between the two (see Reuters Health report, February 7, 2001).

There are currently no data to suggest that the increased risk of developing CHD associated with dental infection is reversible, Dr. P. P. Hujoel and colleagues, of the University of Washington, in Seattle, write in the Journal of the American Dental Association for July.

To investigate further, the researchers identified 1857 individuals with periodontitis and 2170 edentulous subjects, according to the NHEFS database. After 17 years of follow-up, 1238 CHD events, including myocardial infarction, coronary revascularization or removal of coronary obstruction, were documented, including 538 that were fatal.

The relative risk of experiencing CHD events was 1.02 for those who were edentulous compared with those with periodontitis, after adjusting for demographic variables and cardiovascular risk factors. Adding a time-dependent covariate produced no evidence of a decreased risk of CHD associated with absence of dental infections.

"Our findings are consistent with the hypothesis that the presence of periodontitis may occur coincidentally with, but does not cause, increased cardiovascular risk," Dr. Hujoel said in an American Dental Association statement.

Dr. Hujoel and his colleagues recommend that "unless evidence becomes available that the hypothesized CHD-preventive benefits of eliminating dental infections outweigh the known cardiovascular risks of dental treatments, dental procedures should not be recommended for the purpose of lowering CHD risk."

J Am Dent Assoc 2001;132:883-889.

-Westport Newsroom 203 319 2700

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