LONDON (Reuters Health) – While there was a threefold increase in the incidence of testicular cancer in Denmark between 1945 to 1995, results of a population-based study indicate that this increased risk is not linked to the wider use of disposable nappies (a.k.a., diapers) as had been hypothesised.
Dr. Henrik Mרller from King's College London collected data on 296 Danish men with testicular cancer and 287 controls, for whom data were available on disposable diaper use. Cases and controls were born between 1946 and 1970, and cancer diagnoses were made between 1986 and 1988, according to the report in the January issue of the Archives of Disease in Childhood.
"Men born around 1963 had an estimated 2.5-fold higher lifetime risk of testicular cancer than men born around 1943," Dr. Mרller reports.
Year of birth strongly influenced the frequency of disposable diaper use, with almost no use before 1960. Rates increased from 4.3% among controls and 7.8% among cases in the 1961-1965 birth cohort, up to corresponding rates of 24.0% and 17.2% in the 1966-1970 cohort.
Dr. Mרller says that "the computed odds ratios, which are estimates of the relative risk of testicular cancer in users of disposable nappies [diapers] compared with non-users, were all below unity, indicating a lower risk of testicular cancer in users than in non-users."
Although not providing definitive proof, Dr. Mרller concludes that "the available evidence suggests that the record increase in testicular cancer incidence in Denmark is unlikely to be attributed to the increasing use of disposable nappies in this population."
LONDON (Reuters Health) – While there was a threefold increase in the incidence of testicular cancer in Denmark between 1945 to 1995, results of a population-based study indicate that this increased risk is not linked to the wider use of disposable nappies (a.k.a., diapers) as had been hypothesised.
Dr. Henrik Mרller from King's College London collected data on 296 Danish men with testicular cancer and 287 controls, for whom data were available on disposable diaper use. Cases and controls were born between 1946 and 1970, and cancer diagnoses were made between 1986 and 1988, according to the report in the January issue of the Archives of Disease in Childhood.
"Men born around 1963 had an estimated 2.5-fold higher lifetime risk of testicular cancer than men born around 1943," Dr. Mרller reports.
Year of birth strongly influenced the frequency of disposable diaper use, with almost no use before 1960. Rates increased from 4.3% among controls and 7.8% among cases in the 1961-1965 birth cohort, up to corresponding rates of 24.0% and 17.2% in the 1966-1970 cohort.
Dr. Mרller says that "the computed odds ratios, which are estimates of the relative risk of testicular cancer in users of disposable nappies [diapers] compared with non-users, were all below unity, indicating a lower risk of testicular cancer in users than in non-users."
Although not providing definitive proof, Dr. Mרller concludes that "the available evidence suggests that the record increase in testicular cancer incidence in Denmark is unlikely to be attributed to the increasing use of disposable nappies in this population."
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