Antibody Prevents Experimental Choroidal Neovascularization

NEW YORK (Reuters Health) Mar 20 – Intravitreal injection of a recombinant monoclonal antibody directed toward vascular endothelial growth factor (VEGF) prevents choroidal neovascularization in a monkey model, according to a report in the March Archives of Ophthalmology.
"Neovascular age-related macular degeneration (AMD) (and other causes of choroidal neovascularization) is a significant public health problem, leading to severe vision loss in a large number of people," Dr. Joan Miller from the Massachusetts Eye and Ear Infirmary in Boston, Massachusetts told Reuters Health. "Two hundred thousand cases of severe vision loss from AMD are estimated to occur yearly in the U.S. alone, and physicians have had little to offer in the way of treatment."

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