Avocado/Soybean Derivative Does Not Have Major Effect in Hip Osteoarthritis

NEW YORK (Reuters Health) Mar 26 – The anti-osteoarthritic effect of avocado/soybean unsaponifiables (ASU) seen in preclinical tests have not been borne out, overall, in a randomized clinical trial. However, ASU did seem to reduce in patients with advanced joint space narrowing.
In a 2-year, randomized, double-blind, placebo-controlled trial, Dr. Michel Lequesne, of Hopital Leopold Bellan, Paris, and colleagues examined the effect of ASU in a randomized trial involving 163 patients with symptomatic osteoarthritis of the hip and a joint space of at least 1 mm. The subjects were assigned to take one 300-mg capsule of ASU or a placebo capsule for 2 years.

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