Three months of moderate aerobic exercise did not improve insulin sensitivity in obese men with type 2 diabetes taking oral hypoglycemic agents. However, non-obese diabetics did show increased insulin sensitivity with exercise.
The study was conducted by investigators at the Quebec Heart Institute at Laval Hospital in Quebec City, Quebec, Canada.
Six non-obese and seven obese men with type 2 diabetes treated with oral hypoglycemic agents participated in a 12-week ergocycle program at 60 percent VO2 peak for one hour a day, three times a week. Diet and medication were unchanged during the study. The investigators assessed insulin sensitivity using the euglycemic hyperinsulinemic clamp technique.