04/01/2002
By James Adams
A quick and sensitive method for identifying children with meningococcal septic shock who are at risk of death has been developed by Spanish investigators.
Prognostic scores using the new method provided the best discriminative capability in comparisons with the Glasgow Meningococcal Septicaemia Prognostic Score, Malley score and the Paediatric Index of Mortality, according to the investigators.
Pediatric intensive care units at 14 different tertiary hospitals, including the Pediatric Intensive Care Unit of the Residencia Cantabria and the University of Cantabria in Santander, Spain, were involved in the development and validation of the new scoring method.
The new score was developed using clinical and laboratory data gathered in the first two hours after admission from 192 children consecutively admitted from 1983 to 1995 with presumed or confirmed meningococcal septic shock. It was validated in a sample of 158 children consecutively admitted from 1996 to 1998.
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