Medical Science Monitor
04/04/2002
By David Ball
Increased type 1 plasminogen activator inhibitor level (PAI-1) in patients with dermatitis herpetiformis (DH), a rare bullous dermatitis of autoimmune origin, may reflect a chronic inflammatory condition.
DH patients were found to have lower plasminogen and a-2 antiplasmin levels and increased concentrations of plasmin-alpha-2 antiplasmin (PAP) complexes. The findings suggest increased in vivo plasminogenesis among patients with DH, say researchers at the Medical University of Bydgoszcz, Poland.
The researchers measured indicators of fibrinolysis in 23 males and 10 females with DH compared to a healthy control group. The indicators included tissue plasminogen activator concentration (t-PA: Ag); urokinase plasminogen activator concentration (u-PA: Ag); plasminogen activator inhibitor concentration (PAI-Ag); plasminogen level; alpha-2 antiplasmin activity (a-2-AP); and PAP.
e-Med Tools
קצר קולע וממוקד
e-Med סמינרים
אי-מד תחקירים
Medscape Tools
Journal Club
מרכזי מידע ושירות
Facebook
מידע למפרסם
מאגר תרופות
מאגר אנשי המקצוע
אינדקס שימושי
חדשות משה"ב
eMed HealthClub
מחקרים קליניים
השאירו תגובה
רוצה להצטרף לדיון?תרגישו חופשי לתרום!