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AAN: Statins Provide no Neurological Protection during Bypass Surgery

By Ed Susman

Special to DG News

DENVER, CO — April 18, 2002 — Researchers say they could not find any link between statin use and protection against neurological events among patients undergoing coronary artery bypass surgery.

"Our observations do not support the hypothesis that statins may prevent stroke or neurological dysfunction after coronary artery bypass graft surgery," said Lucas Restrepo, MD, a research fellow at the Johns Hopkins University School of Medicine, Baltimore. However, Dr. Restrepo said the study might have been too small to find a significant correlation between the two.

In his report here today at the 54th annual meeting of the American Academy of Neurology, Dr. Restrepo noted that statin drugs appear to reduce the risk of stroke by 19 to 32 percent in patients with coronary artery disease, with benefits that appear to extend beyond their lipid-lowering. He and his research colleagues attempted to see if statin pre-treatment would decrease neurological events in patients undergoing coronary artery bypass graft surgery (CABG).

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