Is High-Normal Systemic Arterial Blood Pressure Associated With an Increase in Cardiovascular Disease?

J. Willis Hurst, MD

In a new study, Vasan and colleagues[1] sought to determine whether high-normal blood pressure is associated with an increase in cardiovascular disease. They used the standard definition of high-normal (systolic pressure of 130-139 mm Hg and diastolic pressure of 85-89 mm Hg) and observed 6859 individuals for 10 years.
The incidence of cardiovascular disease occurring in individuals aged 35-64 years was 4% (2% for women and 6% to 10% for men). In older people — those aged 65-90 years — the incidence was even higher, at 18% (12% to 23% for women and 25% for men). In comparison, the incidence of cardiovascular events in patients with optimal blood pressure was significantly lower than it was for patients with high-normal blood pressure.

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