Regular endurance exercise training helpful in men with poor lipid profiles

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Last Updated: 2001-07-17 15:21:14 EDT (Reuters Health)

WESTPORT, CT (Reuters Health) – Regular endurance exercise training is beneficial for men with poor lipid profiles, particularly for those with high triglyceride (TG) and low HDL-cholesterol levels, according to a report published in the July issue of Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association.

Dr. Jean-Pierre Despres, from the Quebec Heart Institute, in Sainte-Foy, and colleagues assessed the impact of a 20-week endurance exercise training program on the lipid profiles of 62 men with normolipidemia, 38 men with isolated low HDL levels, 38 men with isolated high TG levels, and 62 men with high TG and low HDL levels.

Men in the high TG/low HDL group showed a significant increase in HDL cholesterol levels, while men with isolated low HDL levels did not, the authors report. All men with elevated TG levels showed a significant reduction in plasma TGs, but only men in the high TG/low HDL group showed a significant reduction in apolipoprotein B levels at the end of the study, the investigators point out.

The only significant correlate of the improved lipid profile in men with high TG/low HDL levels was an exercise-induced change in abdominal subcutaneous adipose tissue, the researchers note.

"Results of the present study suggest that regular endurance exercise is particularly helpful to improve the lipid lipoprotein profile of men with low HDL-cholesterol levels along with abdominal obesity and elevated TG concentrations," the authors conclude.

"It appears that subjects with low HDL-cholesterol levels as an isolated trait are much less responsive to endurance exercise training," a finding that is consistent with clinical observations, Dr. Despres' team notes.

Arterioscler Thromb Vasc Biol 2001;21:1226-1232.

-Westport Newsroom 203 319 2700

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