Colposcopy Recommended For Women With Persistent Grade I or II Pap Results

Colposcopy with histologic assessment should be the standard of care for women with persistent grade I or II cervical intraepithelial neoplasia (CIN) and cancer.

Conservative management of their care should be discouraged, European researchers say.

They found a high rate (31.2 percent) of underlying prevalent grade III CIN in a study of women with repeated Papanicolaou tests classified as grade I or II CIN and who tested positive for human papillomavirus (HPV).

German and British investigators comment: "The high rate of underlying prevalent grade III CIN and cancer found in our study indicates that conservative management of women with persistent grade I or II CIN should be discouraged.

"Colposcopy with histologic assessment should be recommended as the standard of care.

"However, for women with histologically proven grade I or II CIN, subsequent conservative management was safe in our study for those who were negative for HPV by type-specific polymerase chain reaction (PCR)."

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