Four Weeks of Enoxaparin Prophylaxis Best

NEW YORK (MedscapeWire) Mar 28 — In orthopaedic surgery, 4 weeks of prophylaxis with low molecular weight heparin is more effective than 1 week for the prevention of venous thromboembolism. Results of a trial published in the March 28 issue of the New England Journal of Medicine suggest that the same is true following abdominal or pelvic surgery for cancer.
"Enoxaparin prophylaxis for four weeks after surgery for abdominal or pelvic cancer is safe and significantly reduces the incidence of venographically demonstrated thrombosis, as compared with enoxaparin prophylaxis for one week," write David Bergqvist, MD, PhD, and colleagues in the Enoxaparin and Cancer (ENOXACAN II) study.

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