Drug-Eluting Stent Shows Less Effect Over Time

DALLAS, TX — April 2, 2002 — A new drug-eluting stent — a tiny spring device coated with medicine that keeps blood vessels from reblocking after angioplasty — may have a problem holding up over time, say researchers in today's rapid access publication of Circulation: Journal of the American Heart Association.

"The positive results at six months were not maintained at 12 months," says the study's lead author Antonio Colombo, MD, Centro Cuore Columbus Hospital, Milan, Italy.

Drug-eluting stents contain chemicals that inhibit cell growth in the inner layer of the artery wall. This prevents in-stent restenosis, which can cause a heart attack. In the past, doctors have used lasers, drugs and other techniques to prevent restenosis.

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