British Journal of Anaesthesia (BJA)
By Mark Moran
Perioperative administration of dexketoprofen appears to markedly improve pain and decrease morphine use following hip arthroplasty, according to researchers at Cork University Hospital and National University of Ireland, Cork, Republic of Ireland.
Visual analogue pain scores and cumulative morphine consumption were both significantly lower among hip arthroplasty patients receiving perioperative dexketoprofen, compared to a matched control group receiving placebo. Increases in postoperative concentrations of plasma interleukin 6 concentrations were also significantly lower in the treated group.
In addition, scores for nausea, vomiting and sedation were lower in the treated group, the researchers say.