גסטרואנטרולוגיה

SAGES: Stretta Procedure for GERD Proves Successful After Three to Six Months

NEW YORK, NY — March 15, 2002 — In 41 patients undergoing the Stretta procedure for gastroesophageal reflux disease, 18 of 29 (62 percent) examined after three months and 10 of 17 (56 percent) examined after six months had stopped taking proton pump inhibitors.

Hugh Houston, MD, and colleagues from Vanderbilt University Medical Center, Nashville, Tennessee, reported their results here yesterday at the 8th World Congress of Endoscopic Surgery (SAGES).

Forty-one patients underwent the procedure on an outpatient basis and were evaluated prospectively. They were studied pre- and postoperatively with esophageal manometry, 24-hour pH testing, Short Form 12 (SF12) surveys, and GERD-specific questionnaires (QOLRAD).

Thirty-three procedures were performed under conscious sedation and eight under general anesthesia. Prior to the procedure, mean lower esophageal sphincter (LES) pressure was 24.3 ± 2.9 mm Hg, Johnson-DeMeester score was 33.6±4.6 mm Hg, and percent time reflux was 60.5 (p<.01). Physical SF 12 scores also improved significantly at six months, from 26.3±3.2 to 32.7±4.2 (p<.01). Mental SF12 scores improved at three months, from 43.4±2.8 to 52.2±4.0 (p<.03), but not at six months.

Eight patients returned for esophageal manometry and 24-hour pH testing at a mean of 74 months. No significant change occurred in esophageal acid exposure or mean LES pressure. One case of gastroparesis at 10 days postoperatively resolved completely.

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