NEW YORK (Reuters Health) – Men and women whose mothers consumed a high-animal protein, low-carbohydrate diet in late pregnancy tend to have higher blood pressure, according to a report in the December issue of Hypertension: Journal of the American Heart Association.
Dr. David J. P. Barker, of the University of Southampton, UK, and colleagues measured the systolic and diastolic blood pressures of 626 subjects in Motherwell, Scotland, whose mothers' diets were monitored during pregnancy. "The mothers had taken part in a dietary intervention in which they were advised to eat 1 lb. (0.45 kg) of red meat per day and to avoid carbohydrate-rich foods during pregnancy," the investigators explain.
The offspring of women who reported greater consumption of meat and fish in late pregnancy had higher systolic blood pressure in adult life (regression coefficient, 0.19 mm Hg per portion per week; p = 0.02). Those whose mothers reported greater consumption of fish, but not meat, had higher diastolic blood pressure in adult life (regression coefficient, 1.00 mm Hg per portion per week; p = 0.02).
"These associations were independent of maternal blood pressure, body size, and smoking habits during pregnancy," Dr. Barker and colleagues report.
They conclude that "these associations may reflect the metabolic stress imposed on the mother by an unbalanced diet in which high intakes of essential amino acids are not accompanied by the nutrients required to utilize them."
Hypertension 2001;38:1282-1288.
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