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Nasal sumatriptan effective for young children

מתוך medicontext.co.il

WESTPORT, CT (Reuters Health) – In young children with migraine, nasal sumatriptan appears to be effective and well tolerated, researchers report.

Dr. Andrew D. Hershey from the University of Cincinnati College of Medicine, in Ohio, and colleagues asked 10 patients, 5 to 12 years old, to treat their migraine headaches with either 5 mg or 20 mg nasal sumatriptan.

Forty-seven of 57 treated headaches (82.5%) responded to sumatriptan, the research team reports in the journal Headache. The mean number of headaches treated was 5.2 per subject and sumatriptan was effective in a mean of 4.3 headaches per subject, the researchers report.

Nasal sumatriptan was ineffective in one child, 50% effective in two children and 100% effective in seven children. Three patients complained of a persistent bad taste, which was the most common side effect.

"For difficult-to-treat or -manage young migraine patients, this opens up another therapeutic option," Dr. Hershey told Reuters Health. He added that "physicians should be willing to try using nasal sumatriptan even though it hasn't gone through formal US Food and Drug Administration approval process for this age group."

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