רוקחות-פרמקולוגיה

Fluoroquinolones Plus Corticosteroids Increases Risk of Achilles Tendon Disorders In Those Over 60

Patients 60 and older who are prescribed fluoroquinolones and corticosteroids have an increased risk of developing Achilles tendon disorders.

 Dr P D van der Linden and colleagues at the Erasmus University Medical Center. Rotterdam, The Netherlands previously found, in a small study, an association between tendinitis and fluoroquinolones.

 The clinicians used a large British family doctor database to carry out this nested case-control study examining the association between these drugs and Achilles tendon disorders. The base cohort consisted of all patients aged 18 years or over who had received a fluoroquinolone.

The cohort included 46,776 users of fluoroquinolones over a six year period, of whom 704 had Achilles tendinitis and 38 had Achilles tendon rupture.

The researchers found that the adjusted relative risk of Achilles tendon disorders with current use of fluoroquinolones was 1.9. The risk for recent and past use was similar to that for no use. The relative risk with current use was 3.2 among patients aged 60 and over and 0.9 among patients aged under 60.

0 תגובות

השאירו תגובה

רוצה להצטרף לדיון?
תרגישו חופשי לתרום!

כתיבת תגובה

מידע נוסף לעיונך

כתבות בנושאים דומים

© ‫ e-Med
 כל הזכויות שמורות

 

התכנים המוצגים באתר זה מיועדים לאנשי צוות רפואי בלבד

אם כבר נרשמת, יש להקליד את פרטי הזיהוי שלך
עדיין לא נרשמת? באפשרותך לבצע רישום כאן
להרשמה לאתר